Genetic Databases > Links to genetic databases A-K

BLOCKS: blocks.fhcrc.org
A database of Blocks multiply aligned ungapped segments corresponding to the most highly conserved regions of proteins.

Christina de Duve Institute of Cellular Pathology (ICP) & Université catholique de Louvain (UCL): www.icp.ucl.ac.be/vikkula

The Dysmorphic Human-Mouse Homology Database (DHMHD): www.hgmp.mrc.ac.uk/DHMHD/dysmorph.html
Consists of three separate databases of human and mouse malformation syndromes together with a database of mouse/human syntenic regions. The mouse and human malformation databases are linked together through the chromosome synteny database. The purpose of the system is to allow retrieval of syndromes according to detailed phenotypic descriptions and to be able to carry out homology searches for the purpose of gene mapping. Thus the database can be used to search for human or mouse malformation syndromes in different ways; by specifying specific malformations or clinical features, or chromosome locations; by Homology; by asking for human syndromes located at a chromosome region syntenic with a specific mouse chromosome region (and vice versa from human to mouse).

ENU Mutagenesis Programme: www.mgu.har.mrc.ac.uk/facilities/mutagenesis/mutabase
A large scale mouse genetics programme to identify new phenotypes of relevance to human disease.

The ENU-Mouse Mutagenesis Screen Project: www.gsf.de/ieg/groups/enu-mouse.html
A research centre set up to perform a large ENU mutagenesis in mice with the larger German Human Genome Project (GHGP): www.dhgp.de

European Bioinformatics Institute (EMBL): www.ebi.ac.uk/embl/index.html
EMBL nucleotide sequence database constitutes Europe's primary nucleotide sequence resource which is a result of direct submissions by individual researchers, genome sequencing projects and patent applications. The database is produced in an international collaboration with GenBank (USA) and the DNA Database of Japan (DDBJ). Each of the three groups collects a portion of the total sequence data reported worldwide, and all new and updated database entries are exchanged between the groups on a daily basis.

European Concerted Action on Congenital Anomalies and Twins (EUROCAT): www.eurocat.ulster.ac.uk
Provides baseline epidemiologic information on congenital anomalies in Europe and to assess the impact of known or suspected risk factors. Provides a database for aetiologic or clinical research with close links to BIOMED. The first edition of the "EUROCAT Special Report: Review of Environmental Risk Factors for Congenital Anomalies " is now available on the website at  www.eurocat.ulster.ac.uk/pubdata

European Science Foundation: www.esf.org

GDB (Genome Database): www.gdb.org
Stores information about genes and other genomic features.

Genatlas: www.citi2.fr/Genatlas
A catalogue of genes, markers and phenotypes with many links to major data sources.

GeneLoc (formerly the Unified Database [UDB]): //genecards.weizmann.ac.il/geneloc
Integrates information on human genome with emphasis on mapping information. Mapped DNA segments, classified by categories (such as genes, EST clusters, and STSs mapped by various methods) are presented on a Megabase-scale integrated map, with further links to relevant databases.

Gen Bank: www.ncbi.nlm.nih.gov/Genbank/GenbankOverview.html
Genetic sequence database, collection of publicly available DNA sequences.

GeneCards: http://bioinfo.weizmann.ac.il/cards
The GeneCards database integrates biomedical information into one Web-accessible knowledge base. The GeneCards Encyclopedia integrates a subset of the information stored in major data sources dealing with human genes and their products (with a major focus on medical aspects).

GXD (Gene Expression Database): www.informatics.jax.org/mgihome/GXD/aboutGXD.shtml
The Gene Expression Database (GXD) is a community resource for gene expression information from the laboratory mouse. GXD stores and integrates different types of expression data and makes these data freely available in formats appropriate for comprehensive analysis.

GeneLynx: www.genelynx.org
A portal to a collection of hyperlinks for each human gene.

GeneNote: genecards.weizmann.ac.il/genenote
The Gene Normal Tissue Expression database at the Weizmann Institute of Science.

GeneTests (formerly GeneClinics): www.ncbi.nlm.nih.gov/SNP
A clinical information resource relating to genetic testing to the diagnosis, management, and genetic counselling of individuals and families with specific inherited disorders.

Genome Data Base (GDB): www.gdb.org
Official repository for genomic mapping data at Johns Hopkins University, Baltimore, MD; contains links to OMIM and enzyme databases.

HGMD (Human Gene Mutation Database): archive.uwcm.ac.uk/uwcm/mg/hgmd0.html
Information about disease-causing mutations in genes.

HUGO (Human Gene Nomenclature Committee): ash.gene.ucl.ac.uk/nomenclature
Central clearing house for assigning gene names.

HomoloGene: www.ncbi.nlm.nih.gov/HomoloGene
A resource of curated and calculated orthologs for genes as represented by UniGene or by annotation of genomic sequences.

Human Gene Mutation Database (HGMD): archive.uwcm.ac.uk/uwcm/mg/hgmd0.html
Catalogue of known gene mutations associated with inherited diseases developed at the Institute of Medical Genetics, Cardiff, Wales.

Induced Mutant Resource (IMR): www.jax.org/imr/
The Induced Mutant Resource (IMR) at The Jackson Laboratory was established in September, 1992, and currently serves as the national clearinghouse for the collection and distribution of genetically engineered mice. Genetically engineered strains of mice (mice altered by gene transfer (transgenics), homologous recombination (gene targeting), and chemical mutagenesis) provide powerful new tools for biomedical research. The use of these strains has become important and critical for basic research and for investigating the cause and treatment of human disease. The rapid generation of these strains has created the need for a central facility to collect and distribute them to the scientific community.

Information for Genetic Professionals: www.kumc.edu/gec/geneinfo.html
General information for genetic counsellors, clinical geneticists, with links to research and teaching developed at University of Kansas Medical Centre, Kansas City, KS. Links to professional genetic societies, clinical and research resources.

International Birth Defects Monitoring Systems (IBDMS): www.icbd.org/index.html
Provides a forum for the rapid communication of information among the various birth defects monitoring or surveillance programmes around the world.

International Database of Craniofacial Anomalies: www.icbd.org/WHOIDCFA/idcfa_invitation.htm

InterPro: www.ebi.ac.uk/interpro
A database of protein families, domains and functional sites in which identifiable features found in known proteins can be applied to unknown protein sequences.

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